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Accession number:  10017
VFB id:  FBbt_00100488    
Neuron name:  LT12
Position of cell bodies:  LCBR-LA
Number of cells:  1
Neuron class:  visual projection neuron, lobula tangential neuron
Innervating regions:  LO4_posterior, PVLP
Presynaptic sites:  PVLP
Postsynaptic sites:   
Direction of information:  centripetal
Laterality:  ipsilateral
Publications:  - Otsuna and Ito (2006) J. Comp. Neurol. 497:928-958
Strains / Antibodies:  NP7365-Gal4
Morphological description:   The LT12 consists of a single neuron, with its cell body in the anterior area of the lateral cell body region (Fig. 1). The cell body fiber bifurcates at the neck of the lobula. The branch toward the lobula arborizes at the posterior edge of the lobula and enters the neuropil tangentially in the LO4 layer (Fig. 1, the middle panel). The area of arborization is limited only in the posterior half of the visual field (Fig. 1, the right panel). The branch toward the central brain projects to the vlpr along the lobula/lobula plate bundle (Fig. 1). It terminates in the medial vlpr without forming intense branches (Fig. 3).
The n-syb::GFP signal was observed only in the vlpr (Fig. 3). Like LT1, 10, and 11, LT12 is therefore centripetal.
(Otsuna and Ito, 2007)
Functional description:   
Figure 1:  
3D stereograms from three viewing angles. Arrowheads indicate the bifurcation point of the cell body fiber. (Neurons other than LT12 are erased from the data. ) Arrows indicate the point where the fiber makes a steep turn. CB, position of the cell bodies; vlpr, ventrolateral protocerebrum; LO4: arborized layers in the lobula.
Modified from Otsuna and Ito (2006).
Figure 2:  
Detailed arborization pattern of LT12. Modified from Otsuna and Ito (2006).
Figure 3:  
Distribution of the presynaptic sites. Staining with the presynaptic site-targeted n-syb::GFP (green to white) and cytoplasmic DsRed (magenta). White characters with under bar indicate the areas of arborizations with presynaptic sites. Modified from Otsuna and Ito (2006).
File 1:  
QTVR movie, from Otsuna and Ito (2006).

Static link to this record :  https://flybrain-ndb.VirtualFlyBrain.org/neuronrec-10017.html
This record was added by Kazunori Shinomiya on 02/04/2010.